Not provided by employer
Patch bio engineers dna for gene therapyWe build technology to make gene therapies safer and more effective, and able to address a broader range of diseasesTo do that, we work at the interface of genomics, machine learning, and dna synthesisWe are a seed-stage, venture-backed biotech startup based in new york city.
You will be responsible for training ml models using data from our massively parallel assays in order to design large libraries of candidate dna/rnaIdeally, you have experience in quantitative genomics applications, including training neural networks to predict functional properties of sequences.
Develop our core ml engine for exploring sequence space and designing new candidate elements for large functional screens.
Work with our wet lab scientists to ground your designs in experimental considerations.
Process ngs data to quantify activity of individual library elements and train predictive models on dna sequences.
Curate relevant external datasets and integrate with our internal data.
Phd in computational biology, genomics, biomedical engineering, computer science, or equivalent
Solid training and expertise in genomics, as evidenced by experience with ngs data.
Knowledge of and experience with machine learning, including neural network frameworks (e.g., pytorch or tensorflow) and state-of-the-art network architectures.
Familiarity with nucleic acid design, including issues related to biochemistry (secondary structure, gc content, repetitiveness), and other factors that affect experimental concerns.
Experience working successfully in collaborative, multidisciplinary teams.
Desire to work in a rapidly growing company, and a fast-changing environment.
Knowledge of gene/protein expression regulation
Design of mpra
Experience collaborating with wet lab scientists in experimental design
Software engineering best practices, potentially through industry experience
Life at patch
In this formative stage of the company, you will have a large impact on many of the key decisions that will define our long-term pathYou will join a team of curious and creative experts passionate about making a difference for patientsYou will help shape a diverse and inclusive culture, with competitive benefits including great healthcare, generous time off, flexible hours, and access to a 401(k).
Our lab is in the heart of soho, nyc, but if you don`t need to be at the bench you can work from wherever you please.
If you share our enthusiasm with working on a fascinating problem at the intersection of synthetic biology and machine learning, that will significantly impact millions of patients, come join us!
To learn more, please email firstname.lastname@example.org.
Posted 30+ days ago